New Study Finds Statins Increase Risk For Diabetes

New Study Finds Diabetes Risk Rises With Statin Use

The risk of new-onset type 2 diabetes rises with adherence to statin therapy, providing further confirmation of the previously reported link.


The findings were published online June 26 in Diabetes Care by Giovanni Corrao, PhD, of the division of biostatistics, epidemiology, and public health, University of Milano-Bicocca, Milan, Italy, and colleagues.

Here is another of the many health conditions caused by people taking statins

The study, involving a healthcare database of 115,709 statin-using patients with an average 6.4 years of follow-up per patient, “extends earlier findings of an increased risk of diabetes with statin therapy by providing evidence of a clear-cut association between adherence to statin therapy and risk of new-onset diabetes in a real-world setting,” Dr Corrao and colleagues write.

This study further supports the conclusion of a recent clinical trial review from the diabetes subpanel of the US National Lipid Association Expert Panel on Statin Safety that came to the conclusion that using cholesterol lowering statin drugs increased the chances of getting type 2 diabetes.

No Difference Between Different Potency Statins

In the new study, the patients had a mean age of 62 years at the time of first statin prescription. None had been diagnosed with diabetes prior to that time. During follow-up, 9.6% of the entire cohort developed diabetes, at a rate of 14.9 per 1000 person-years.

Statins used by participants included simvastatin, pravastatin, fluvastatin, atorvastatin, and rosuvastatin (Crestor, AstraZeneca): a separate analysis of high- vs low-potency statins did not show a statistically significant difference in the statin effect on diabetes risk.