Gut Immune System

Animation: Gut Immune System Explained


Gut Immune System Importance

The gut immune system mucosa is the largest and most dynamic immunological environment of the body. Containing about 80% of all our immune system cells, it’s often the first point of pathogen exposure and many microbes use it as an entry point into the rest of the body. The gut immune system therefore needs to be ready to respond to pathogens but at the same time the gut immune system is constantly exposed to innocuous environmental antigens, food particles and harmless microflora which need to be tolerated without causing the gut immune system to attack.

Improper pathological immune system responses in the gut to harmless antigens may be a major factor in many debilitating conditions such as Crohn’s disease, Rheumatoid Arthritis, Multiple Sclerosis, Sjogren’s, Hashimoto’s Thyroiditis, Grave’s disease, Psoriasis, Eczema, Amyotrophic Lateral Sclerosis (Lou Gehrig’s disease) many other autoimmune diseases.

This animation introduces the key cells and molecular players involved in gut immuno-homeostasis and disease.


80% of our Immune System cells are located within the Gut!

Immunity from disease begins in the GUT!