Expired Influenza Vaccine Being Given To Patients

Expired Live Attenuated Influenza Vaccine Being Administered

Around 20% or more of intra-nasally administered influenza vaccine may be expired.  expired influenza vaccine

A recent report notes: “annual influenza vaccination is recommended for all persons aged ?6 months. Two vaccine types are approved in the United States, injectable inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV), which is administered intranasally.” 

“Influenza vaccine typically becomes widely available beginning in late summer or early fall. IIV has a standard expiration date of June 30 for any given influenza season (July 1 through June 30 of the following year).”

“In contrast, after release for distribution, LAIV generally has an 18-week shelf life …. Because of its relatively short shelf life, LAIV might be more likely than IIV to be administered after its expiration date. To assess that hypothesis, CDC analyzed reports to the Vaccine Adverse Event Reporting System (VAERS) of expired LAIV administered during July 1, 2007, through June 30, 2014.”

“Of the 4,699 LAIV reports, 866 (18.4%) involved administration of expired vaccine.”

“As a passive surveillance system, VAERS likely captures only a small fraction of expired LAIV administered, so this error might be more common than VAERS data indicate. Most reports had a vaccination date in November or later. Health care providers need to be aware of the short shelf life of LAIV and implement measures to avoid administering expired LAIV, especially from November and onward, when this error appears to be more common”

Source: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6335a3.htm